What is a BAC library? BAC stands for Bacterial Artificial Chromosome. These are small, often circular, pieces of bacterial DNA that can be identified and copied within a bacterial cell. They …

BAC（细菌人工染色体）文库和PAC（P1-derived Artificial Chromosome，P1人工染色体）文库是基本遗传工具，主要用于基因组测序、构建物理图谱、染色体步查、基因筛选和基因图位克隆 …

Bacterial artificial chromosome (BAC) libraries play a crucial role in the development of fluorescence in situ hybridization (FISH) probes. A BAC is created fragmenting genomic DNA …

2024年5月13日 · BAC是一种装载DNA大片段的克隆载体系统，用于人、动物和植物基因组文库构建。 BAC具有插入片段较大 (几千个碱基至350kb)、嵌合率低、遗传稳定性好、易于操作等优 …

Large-insert genomic DNA libraries in bacteria, such as bacterial artificial chromosome (BAC; Shizuya et al. 1992) and P1-derived artificial chromosome (PAC; Ioannou et al. 1994) libraries, …

2012年2月16日 · Large-insert BAC (bacterial artificial chromosome) and BIBAC (binary BAC) libraries are essential for modern genomics research for all organisms.

It involves the use of fluorescently labeled probes that bind to complementary target sequences, allowing researchers to identify and locate specific genes or regions of interest. Bacterial …

2007年6月28日 · Bacterial artificial chromosome (BAC) libraries are the large DNA insert libraries of choice and valuable tools for the map-based cloning of target quantitative...

Bacterial artificial chromosome (BAC) is a kind of vector system used to construct large fragment insert libraries of genome DNA in human, animals and plants. Bacterial artificial chromosome …

1997年5月20日 · We have constructed a human genomic bacterial artificial chromosome (BAC) library using high molecular weight DNA from a pre-pro-B cell line, FLEB14-14, with a normal …