Tumor antigen - Wikipedia
Examples of tumor-specific antigens include the abnormal products of ras and p53 genes. In contrast, mutation of other genes unrelated to the tumor formation may lead to synthesis of abnormal proteins which are called tumor-associated antigens.
Tumor Antigens - Tumor Antigens - MSD Manual Professional …
Cancer-associated or cancer-specific antigens have been identified in most of the human cancers, including Burkitt lymphoma, neuroblastoma, melanoma, osteosarcoma, renal cell cancer, breast cancer, prostate cancer, lung cancer, and colon cancer.
Uncovering the Tumor Antigen Landscape: What to Know about …
Naturally presented antigens in the human leucocyte antigen-1 (HLA-I) complex on the tumor surface are the main protagonists in evocating a specific anti-tumor CD8+ T cell response. However, the methodologies for their identification have been a major bottleneck for their reliable characterization.
Tumor Antigen - an overview | ScienceDirect Topics
Antigens used for anti-tumor immunity must be chosen carefully from examples that are (i) unique to tumors, (ii) highly expressed in tumor cells, minimizing the normal tissue damage, or (iii) expressed on healthy cells that may be deleted for some time without major complication (eg, B …
Examples of common tumor antigens. | Download Table
Dendritic cells (DCs) are potent antigen-presenting cells (APCs) that play a critical role in the induction of antitumor immunity. Therefore, various strategies have been developed to deliver...
Tumor Antigens - Holland-Frei Cancer Medicine - NCBI Bookshelf
For something to be a tumor antigen, it must be recognized by specific immune effector cells and/or antibodies and be produced by tumor cells. Among the tumor antigens, some may be tumor specific while others may also be expressed by normal tissues.
Tumor Antigen - an overview | ScienceDirect Topics
Tumor antigens are surface molecules that are mostly cancer specific, often overexpressed and recognized by the immune system. Therefore, identifying tumor antigens is of key importance for developing new immunotherapies for incurable cancers.
Tumor Antigen - an overview | ScienceDirect Topics
These antigens are classified into four types based on their origin or expression profile: universal tumor antigens (expressed in most tumor cells, such as telomerase and survivin), cancer-testis antigens (found in both cancer cells and testicular cells, such as MAGE and RAGE), tissue-specific antigens (involved in tissue differentiation and are...
Categories of Tumor Antigens - Holland-Frei Cancer Medicine
Examples of tumor-associated antigens that fall into each of these categories are provided in Table 12-1. General Categories and Examples of Tumor Antigens. It should be stressed that these categories are not mutually exclusive and tumor antigens may fall …
Tumor Antigens - Hematology and Oncology - Merck Manual …
Cancer-associated or cancer-specific antigens have been identified in most of the human cancers, including Burkitt lymphoma, neuroblastoma, melanoma, osteosarcoma, renal cell cancer, breast cancer, prostate cancer, lung cancer, and colon cancer. A key role of the immune system is detection of these antigens to permit subsequent targeting for ...