2024年1月14日 · Plasma lipoproteins can be divided into seven classes based on size, lipid composition, and apolipoproteins (chylomicrons, chylomicron remnants, VLDL, VLDL remnants (IDL), LDL, HDL, and Lp (a)). Chylomicron remnants, VLDL, IDL, LDL, and Lp (a) are all pro-atherogenic while HDL is anti-atherogenic.

Lipoprotein classes: Ideally, the lipoprotein assemblies should be described in terms of the main protein components known as apoproteins (or 'apolipoproteins'), as these determine the overall structures and metabolism and the interactions with receptor molecules in …

Apolipoproteins are proteins that bind lipids (oil-soluble substances such as fats, cholesterol and fat soluble vitamins) to form lipoproteins. They transport lipids in blood, cerebrospinal fluid and lymph. The lipid components of lipoproteins are insoluble in water.

Plasma lipoprotein particles are commonly divided into five main classes, based on size, lipid composition, and apolipoprotein content: HDL, LDL, IDL, VLDL and chylomicrons. Subgroups of these plasma particles are primary drivers or modulators of atherosclerosis .

Human plasma lipoproteins are commonly divided into six major classes. Chylomicrons are the largest lipo- proteins (>lo0 nm in diameter). They are synthesized by the intestine to transport dietary triglyceride and cholesterol from the site of absorption in the intestinal epithelium to various cells of the body.

2002年1月1日 · The lipoproteins within each class are heterogeneous in terms of their density, size, and lipid and apolipoprotein contents and compositions, as well as in their functional 485 properties. They can be separated into subclasses by ultracentrifugation, gel filtration, electrophoresis, or affinity chromatography methods.

2024年1月14日 · Plasma lipoproteins can be divided into seven classes based on size, lipid composition, and apolipoproteins (chylomicrons, chylomicron remnants, VLDL, VLDL remnants (IDL), LDL, HDL, and Lp (a)). Chylomicron remnants, VLDL, IDL, LDL, and Lp (a) are all pro-atherogenic while HDL is anti-atherogenic.

2008年1月1日 · Although the assembly, structure, metabolism, and receptor interactions of lipoproteins are determined by their apolipoprotein components, the most common classifications of lipoproteins are based on their hydrated density or mobility on agarose gel electrophoresis.

1984年12月1日 · Plasma lipoprotein metabolism is regulated and controlled by the specific apolipoprotein (apo-) constituents of the various lipoprotein classes. The major apolipoproteins include apoE, apoB, apoA-I, apoA-II, apoA-IV, apoC-I, apoC-II, and apoC-III.

Plasma lipids are transported by lipoproteins composed of several classes of lipids (including cholesterol, triglycerides, and phospholipids) and proteins designated apolipoproteins. Our understanding of the role of lipoproteins and apolipoproteins in lipid transport has markedly increased over the last two decades.