Cathinone (/ ˈ k æ θ ɪ n oʊ n /; also known as β-ketoamphetamine) is a monoamine alkaloid found in the shrub Catha edulis and is chemically similar to ephedrine, cathine, methcathinone and other amphetamines.

Cathine, also known as D-norpseudoephedrine or as (+)-norpseudoephedrine, is a psychoactive drug of the phenethylamine and amphetamine groups which acts as a stimulant. Along with cathinone, it is found naturally in Catha edulis (khat), and contributes to the overall effects of the plant. [3] Cathine has approximately 7 to 10% of the potency of ...

Synthetic cathinones are derivatives of the naturally occurring compound cathinone, the main psychoactive ingredient in the khat plant Catha edulis. Cathinone is the β-keto analog of amphetamine, and all synthetic cathinones display a β-keto moiety ...

The present paper will focus on synthetic cathinones, which comprise a vast group of compounds derived from cathinone (1), an alkaloid found in khat (Catha edulis) leaves, structurally identical and similar in action to amphetamine (2) .

2024年3月29日 · Synthetic cathinones (SCs) are β-keto analogues of cathinone, with cathinone’s backbone structure having four modification positions, the aromatic ring (R1), alkyl side chain (R2), and amino group (R3 and R4), allowing for the synthesis of a wide range of derivatives [2,3].

Presently, the latest versions of sympathomimetic compounds to emerge as abused drugs are the synthetic cathinones derivatives. Cathinone is a naturally occurring β-ketone analog of amphetamine found in the leaves of the Catha edulis plant indigenous to northeast Africa and the Arabian Peninsula.

2012年6月1日 · Cathine, formally named 1S,2S-norpseudoephedrine, arises from the metabolism of cathinone in the mature plant. This compound, molecular weight of 151.21 g/mol, is one of the optical isomers of phenylpropanolamine producing amphetamine-like effect less potent than cathinone (Schorno and Steinegger, 1979).

2017年6月28日 · Cathinones have different pharmacological activities and receptor selectivity for monoamine transporters based on their chemical structures. They are incorporated into NPS mixtures and used with other NPS or ‘traditional’ drugs. Cathinone use represents significant health risks to individuals and is a public health burden. Methods

2013年12月8日 · Cathinone is the main psychoactive substance found in the leaves of the C. edulis. Chemically, cathinone is the β-keto analog of amphetamine, thus detaining similar main subjective effects, namely euphoria and increased energy. Unwanted clinical effects following khat abuse often include hallucinations, agitation, and anxiety.

Cathine and cathinone were deposited in considerable concentrations in all tissues analyzed, with the highest C max in the lung and T max in the heart tissues but not in the brain. In addition, neurotransmitters such as adrenaline, dopamine, norepinephrine, and serotonin were dif …