Bacterial antigens, whether produced by a viable intrasynovial bacterium or brought into the articular cavity by monocytes, have an immunostimulatory action.These antigens can most likely persist in the joint either “stuck” to the extracellular matrix or within antigen presenting cells [221, 258, 259] and as described above, are able to specifically …

2023年3月30日 · Bacterial capsules are also used as antigens used in vaccines where the polysaccharide component of the capsule is conjugated with protein carriers. The exact structure, function, and involvement of capsules in bacteria differ in …

Bacterial antigen tests have fallen out of favor as a positive result rarely alters therapy, and the test performance is similar to the Gram's stain (Thomson and Bertram, 2001). In addition, the antigen detection tests are less sensitive than bacterial culture, and their diagnostic accuracy varies from institution to institution ( Greenlee and ...

Detection of bacterial antigens is an attractive approach to TB diagnosis, with the theoretical benefits of high specificity, correlation to bacterial burden and independence from immune function. Assays using serum or urine might have particular application in HIV-associated TB, where extrapulmonary disease is common and a large total body ...

Bacterial antigens that are reactive with the InMAD immune serum are precisely the antigens to target in an antigen immunoassay. By employing InMAD, we identified multiple circulating antigens that are secreted or shed during infection using Burkholderia pseudomallei and Francisella tularensis as model organisms.

Large families of antigen-encoding sequences are observed in bacterial, protozoan and fungal pathogens (see table 1), indicating that expansion of the number of antigen encoding genes is a common evolutionary strategy.

Other Bacterial Antigens. Bacterial Background The Morphology and Fine Structure of Bacteria. Related Resources Infection Immunity Infectious Disease ELISA kit. Bacterial cells are between 0.3 and 5 lm in size. They have three basic forms: cocci, straight rods, and curved or spiral rods (Table 1). The nucleoid consists of a very thin, long ...

Subsequently, bacterial antigens are degraded by the proteasome and presented to major histocompatibility class II (MHCII) complexes, thereby stimulating CD8+ T-cell responses [16,65]. This bacterium was regarded as a potential vaccine vector that can generate tumor-specific T-cell responses via the fusion of tumor-associated antigens (TAA) to LLO.

2017年1月25日 · Reverse vaccinology and proteomics technologies have been used to identify protective bacterial antigens. The former was first applied to the identification of seven meningococcal surface protective antigens from among 350 candidates during an 18-month period (Pizza et al., 2000). Protective antigens have also been screened from a variety of ...

2011年8月16日 · Bacterial antigens that are reactive with the InMAD immune serum are precisely the antigens to target in an antigen immunoassay. By employing InMAD, we identified multiple circulating antigens that are secreted or shed during infection using Burkholderia pseudomallei and Francisella tularensis as model organisms.