Bone morphogenetic protein - Wikipedia
Signal transduction through BMPRs results in mobilization of members of the SMAD family of proteins. The signaling pathways involving BMPs, BMPRs and SMADs are important in the …
Bone Morphogenetic Protein (BMP) signaling in development …
2014年9月1日 · Bone Morphogenetic Proteins (BMPs) are a group of signaling molecules that belongs to the Transforming Growth Factor-β (TGF-β) superfamily of proteins. Initially …
Bone Morphogenetic Proteins - PMC
BMP signaling plays important roles in adipogenesis, not only in maturation of pre-adipocytes, but also in commitment of undifferentiated progenitor cells.
TGF-β/BMP signaling and other molecular events: regulation of
2015年4月14日 · Phosphorylation of TGF-β (I/II) or BMP receptors activates intracellular downstream Smads, the transducer of TGF-β/BMP signals. This signaling is modulated by …
The roles and regulatory mechanisms of TGF-β and BMP signaling …
2024年1月24日 · TGF-βs and BMPs transduce signals through SMAD-dependent and -independent pathways; specifically, they recruit different receptor heterotetramers and R …
BMP signalling in skeletal development, disease and repair
2016年2月19日 · In this Review, we describe BMP superfamily signalling in the context of skeletal development and joint morphogenesis, with the premise that the pathway is poised as a …
Making sense of BMP signaling complexity - Cell Press
2022年5月18日 · In this issue of Cell Systems, two studies systematically interrogate the Bone Morphogenetic Protein (BMP) pathway, uncovering mechanisms and consequences of distinct …
The BMP signaling and in vivo bone formation - PMC
2005年8月8日 · Studies from transgenic and knockout mice and from animals and humans with naturally occurring mutations in BMPs and their signaling molecules have shown that BMP …
Specification of BMP Signaling - PMC - PubMed Central (PMC)
Bone Morphogenetic Proteins (BMPs) together with the Growth and Differentiation Factors (GDFs) form the largest subgroup of the Transforming Growth Factor (TGF)β family and …
Bone morphogenetic protein receptors: Structure, function …
2020年9月1日 · Bone morphogenetic proteins (BMPs) are secreted cytokines that control the fate and function of many different cell types. They exert their cellular responses via heteromeric …
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