Oxazole is the parent compound for a vast class of heterocyclic aromatic organic compounds. These are azoles with an oxygen and a nitrogen separated by one carbon. [4] Oxazoles are aromatic compounds but less so than the thiazoles. Oxazole is a weak base; its conjugate acid has a pK a of 0.8, compared to 7 for imidazole.

1,3-oxazole is a five-membered monocyclic heteroarene that is an analogue of cyclopentadiene with O in place of CH2 at position 1 and N in place of CH at position 3. It is a mancude organic heteromonocyclic parent, a monocyclic heteroarene and a member of 1,3-oxazoles.

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Oxazole is a unsaturated five-membered nitrogen, oxygen containing heteroaromatic with a pyridine like nitrogen and an oxygen atom present at 1,3-positions of the ring. From: The Chemistry of Heterocycles, 2019

Oxazole and its derivatives play a very essential role in the area of medicinal chemistry. Oxazole nucleus is heterocyclic five-membered ring that seemed to be investigated in the advancement of novel compounds which shows favorable biological activities.

Oxazole is an important heterocyclic nucleus having a wide spectrum of biological activities which drew the attention of researchers round the globe to synthesize various oxazole derivatives and screen them for their various biological activities.

In this review, we summarize the recent advances of the synthesis of oxazole-containing molecules utilizing the van Leusen oxazole synthesis from 1972, aiming to look for potential oxazole-based medicinal compounds, which are valuable …

Other names: 1,3-Oxazole Permanent link for this species. Use this link for bookmarking this species for future reference. Information on this page: Notes; Other data available: Gas phase thermochemistry data; Condensed phase thermochemistry data; Phase change data; Gas phase ion energetics data; IR Spectrum; Mass spectrum (electron ionization ...

Oxazole is a heterocyclic compound that consists of a five-membered aromatic ring with one oxygen atom and one nitrogen atom. The chemical formula for Oxazole is C 3 H 3 N 1 O 1 , and it is characterized by its distinct structure, which comprises two …

2022年3月8日 · Oxazole-based scaffold and its analogues are well-accepted as promising moieties in the development and progress of novel drugs revealing immense biological and pharmaceutical activities.