
Oxadiazole - Wikipedia
Oxadiazoles are a class of heterocyclic aromatic [1] chemical compounds of the azole family with the molecular formula C 2 H 2 N 2 O. There are four isomers of oxadiazole: 1,2,3-oxadiazole
Oxadiazoles in Medicinal Chemistry | Journal of Medicinal Chemistry
2011年12月19日 · Oxadiazoles are five-membered heteroaromatic rings containing two carbons, two nitrogens, and one oxygen atom, and they exist in different regioisomeric forms. …
Oxadiazole - an overview | ScienceDirect Topics
An oxadiazole is defined as a doubly unsaturated 5-membered ring composed of two carbons, two nitrogens, and one oxygen atom. It is of interest in pesticide chemistry, polymer science, …
Novel 1,2,4-Oxadiazole Derivatives in Drug Discovery - PMC
Oxadiazoles are five-membered heterocyclic compounds containing one oxygen and two nitrogen atoms (historically, they were also known as furadiazoles). Depending on the position of …
3 1,2,4-Oxadiazoles - Chemistry Europe
2025年1月23日 · By integrating insights from recent research, this review aims to provide a comprehensive overview of the role of oxadiazoles in the fight against tuberculosis, paving the …
The Oxadiazole Antibacterials - PMC
The oxadiazoles are a class of antibacterials discovered by in silico docking and scoring of compounds against the X-ray structure of a penicillin-binding protein. These antibacterials …
Oxadiazoles: moiety to synthesis and utilize | Journal of the …
2021年7月6日 · The current compilation covers the synthesis of all regioisomeric forms taking representative examples, medicinal applications of oxadiazoles as an anticancer, vasodilator, …
Oxadiazoles in medicinal chemistry - PubMed
2012年3月8日 · Oxadiazoles are five-membered heteroaromatic rings containing two carbons, two nitrogens, and one oxygen atom, and they exist in different regioisomeric forms. Oxadiazoles …
2. Oxadiazole - PubMed Central (PMC)
Oxadiazole is a five-membered heterocyclic compound containing two nitrogen atoms and one oxygen atom. The 1,3,4-oxadiazole and 1,2,4-oxadiazole have favourable physical, chemical, …
Oxadiazole - an overview | ScienceDirect Topics
The oxadiazoles are a class of antibacterials discovered by in silico docking and scoring of compounds against the X-ray structure of a penicillin-binding protein.
1,3,4-oxadiazole - an overview | ScienceDirect Topics
2012年5月6日 · 1,3,4-Oxadiazoles have a wide range of pharmaceutical and biological activities that include antimicrobial, antifungal, anti-inflammatory, and antihypertensive [183]. In 2015, …
Oxadiazole: A highly versatile scaffold in drug discovery
2022年5月16日 · The present review will guide the way for researchers in the field of medicinal chemistry to design new biologically active molecules based on the oxadiazole nucleus. …
[1, 2, 4]-oxadiazoles: synthesis and biological applications
In the present article synthesis and medicinal applications of [1, 2, 4] oxadiazoles are reviewed. The oxadiazoles have a wide range of applications such as Antitussive, Anti-inflammatory, …
Oxadiazoles, a specific class of heterocyclic compounds, consist of two carbon atoms, two nitrogen atoms, and one oxygen atom. Discovered in 1884 by Tiemann and Krüger, they were …
The oxadiazole antibacterials - PubMed
The oxadiazoles are a class of antibacterials discovered by in silico docking and scoring of compounds against the X-ray structure of a penicillin-binding protein. These antibacterials …
Synthesis of Multifunctional 2-Aminobenzimidazoles on DNA via …
2020年1月30日 · 2-Aminobenzimidazole cores are among the most common structural components in medicinal chemistry and can be found in many biologically active molecules. …
Synthetic Approaches and Pharmacological Activity of 1,3,4-Oxadiazoles …
Compounds containing 1,3,4-oxadiazole cores have a broad biological activity spectrum including antibacterial, antifungal, analgesic, anti-inflammatory, antiviral, anticancer, antihypertensive, …
Alumni - Scripps Research
Thesis: "Part I. 1,3,4-Oxadiazoles in Tandem Diels-Alder, 1,3-Dipolar Cycloaddition Reactions: A Rapid Synthesis of Vinca Alkaloid Motifs. Part II. Exceptionally Potent Inhibitors of Fatty Acid …
European Journal of Organic Chemistry
2025年3月6日 · Corresponding Author. Rambabu Dandela [email protected] Institute of Chemical Technology - Bhubaneswar Campus, Department of Industrial and engineering chemistry, …
Azilsartan decreases renal and cardiovascular injury in the ...
Results: AZL-M demonstrated anti-hypertensive effects along with markedly improved vascular endothelial function in SHROB. In these rats, AZL-M demonstrates strong kidney protective …