Harmine is a beta-carboline and a harmala alkaloid. It occurs in a number of different plants, most notably the Syrian rue and Banisteriopsis caapi. [3] Harmine reversibly inhibits monoamine oxidase A (MAO-A), an enzyme which breaks down monoamines, making it a Reversible inhibitor of monoamine oxidase A (RIMA). Harmine does not inhibit MAO-B. [4]

Harmine (7-methoxy-1-methyl-9H-pyrido[3, 4-b]indole) is a tricyclic beta-carboline alkaloid that was originally isolated from seeds of Peganum harmala in 1847. Harmine has been traditionally used for ritual and medicinal preparations in the Middle East, Central Asia and South America.

Harmine is a tricyclic alkaloid compound in the ß-carboline family. 1 It was originally isolated in 1847 from the seeds of the wild rue, Peganum harmala, but it is found throughout nature in mammals, insects, and marine organisms.

Harmine is a beta-carboline alkaloid well-known for giving Ayahuasca its hallucinogenic effects. Its main sources are the wild plants Peganum harmala (Syrian rue) and Banisteriopsis caapi, which are noted for their therapeutic value.

Harmine is a harmala alkaloid in which the harman skeleton is methoxy-substituted at C-7. It has a role as a metabolite, an anti-HIV agent and an EC 1.4.3.4 (monoamine oxidase) inhibitor. It derives from a hydride of a harman.

2021年3月30日 · Harmine is a β-carboline alkaloid isolated from Banisteria caapi and Peganum harmala L with various pharmacological activities, including antioxidant, anti-inflammatory, antitumor, anti ...

harmine, hallucinogenic alkaloid found in the seed coats of a plant (Peganum harmala) of the Mediterranean region and the Middle East, and also in a South American vine (Banisteriopsis caapi) from which natives of the Andes Mountains prepared a …

2015年3月11日 · A chemical called harmine, which occurs naturally in a number of plants around the world, has been shown to regenerate pancreatic cells lost in diabetes. Type 1 diabetes is characterised by the immune system attacking insulin-producing pancreatic beta cells, while beta cell deficiency has been observed as a contributor to type 2 diabetes.

2020年11月18日 · Compared with harmine, harmine derivatives exhibited similar pharmacological effects such as neuroprotective, antitumor, pest and parasite control, and antiviral effects, conferring higher activity and lower neurotoxicity.

Harmine has many pharmacological activities including anti-inflammatory, neuroprotective, antidiabetic, and antitumor activities. Moreover, harmine exhibits insecticidal, antiviral, and antibacterial effects.