2016年10月26日 · Using MRIs, researchers at Washington University School of Medicine in St. Louis have identified areas in the brains of children with Tourette’s syndrome that appear markedly different from the same areas in the brains of children who don’t have the neuropsychiatric disorder.

2024年9月30日 · The Tourette’s brain shows structural and functional differences, particularly in areas related to movement control and executive function. It’s got a unique neurotransmitter profile, with dopamine and serotonin playing starring roles in the neurochemical drama.

Tourette syndrome (TS) is a common, chronic neuropsychiatric disorder characterized by the presence of fluctuating motor and phonic tics. The typical age of onset is ∼5–7 years, and the majority of children improve by their late teens or early ...

Tics are neurodevelopmental hyperkinetic symptoms typically associated with unpleasant sensory experiences called premonitory urges. Tourette syndrome (TS) is the primary chronic tic disorder for which medical surveillance is most frequently required, and is associated with a complex phenotypical sp …

An analysis of PET scan of patients with Tourette syndrome (TS) revealed that the different clinical manifestations of the disorder are associated with the expression of two distinct metabolic brain networks, which may prove useful as biomarkers for assessing responses to new therapies for TS and related comorbidities.

2021年10月25日 · Previous studies of brain structure in Tourette syndrome (TS) have produced mixed results, and most had modest sample sizes. In the present multicenter study, we used structural magnetic resonance imaging (MRI) to compare 103 children and adolescents with TS to a well-matched group of 103 children without tics.

Tourette Syndrome (ts) is a developmental neuropsychiatric disorder of the central nervous system defined by the presence of chronic tics. While investigations of the underlying brain mechanisms have provided valuable information, a complete understanding of the pathophysiology of ts remains elusive.

Traditional neuropathologic methods have provided only limited insight into the central nervous system abnormalities underlying Tourette syndrome. In the past 20 years, investigators have turned increasingly to in vivo neuroimaging approaches to localize, quantify, and characterize neuroanatomic, fu …

2022年1月1日 · An increased connectivity of shorter-range connections, including the sensorimotor loop of the cortico-basal ganglia circuitry, has been associated by meta-analyses with the diagnosis of Tourette syndrome (TS). Immaturity of brain development in TS is also reflected by a disconnection of the fronto-parietal network (long-range connection).

2020年10月1日 · Routine neuroimaging such as T1-weighted or T2-weighted magnetic resonance imaging (MRI) studies of the brain are usually normal in patients with GTS. However, the use of advanced functional and structural neuroimaging has …