Find a helpful TNKase® (tenecteplase) dosing guidelines chart for acute ST elevation myocardial infarction treatment with the simple weight-tiered TNKase® dosing. Please see full Prescribing Information for additional important safety information.

Tenecteplase Dilution, Dosing & Admin Information Acute Ischemic Stroke Dilution Instructions: 5 mg/mL • Dilute 50 mg vial with 10 mL preservative free sterile water to = • SWIRL GENTLY DO NOT SHAKE.

• MAX dose of Tenecteplase is 25 mg (5 mL of reconstituted solution) • Tenecteplase can precipitate if giving in an IV line with dextrose • It is recommended to flush before and after dose with NS

Doses tenecteplase (a type of tPA) for use in ischemic stroke. Tenecteplase approval and recommendations for use vary by country. In the US, tenecteplase use in ischemic stroke is off-label. This calculator is for use in ischemic stroke patients only. Do NOT use for calculating doses in STEMI or PE. Please fill out required fields. Other creator.

Dose. Usual Adult: Patient will receive a single bolus dose of tenecteplase 0.25mg/Kg (maximum dose 25 mg) over 5 seconds. Flush IV with normal saline prior to and following administration to ensure full delivery of drug dosage. Mixing/Administration of Tenecteplase. Draw up all diluent from the vial and slowly inject into powder.

• Tenecteplase superior to Alteplase in EXTEND-IA TNK and meta-analyses of previous RCTs demonstrate non-inferiority with Alteplase • Tenecteplase is easier to administer and can facilitate treatment/transfer • Delivered as 5 second push without an …

Nov 8, 2024 · Tenecteplase (TNKase) for Acute Ischemic Stroke can be order using the following: • Ischemic Stroke Tenecteplase IV Administration Order Set OR • Stroke Tenecteplase IV Administration Order Set Dosing Instructions: • Tenecteplase IV push 0.25 mg/kg actual body weight (Max dose 25 mg/5 mL), round to the nearest 1 mg (2 mL) –Refer to ...

Tenecteplase is hepatically metabolised demonstrating a biphasic clearance with an initial half-life of 22 minutes, and a terminal half-life of 90-130 minutes. Thrombolysis of acute STEMI within 12 hours of symptom onset, where percutaneous coronary intervention is …

Maximum dose for acute ischemic stroke is 25 mg Mixing: TNK comes in a kit – follow manufacturer’s instructions Total concentration of TNK per vial is 5mg/ml

Obtain and document accurate weight for dosing. Verify total dose to be administered. Develop consistent process for administering. Include a 5ml syringe alongside the box (kit) for more accurate and safe dosing (see Tenecteplase kit images below). Round the …