Enterobacteria phage T2 is a virus that infects and kills E. coli. It is in the genus Tequatrovirus, and the family Myoviridae. Its genome consists of linear double-stranded DNA, with repeats at either end. The phage is covered by a protective protein coat.

2025年1月11日 · In 1952 Alfred Day Hershey and Martha Chase used the T2 bacteriophage in a famous experiment in which they demonstrated that only the nucleic acids of phage molecules were required for their replication within bacteria. The results of the experiment supported the theory that DNA is the genetic material.

The caudal sheath of bacteriophage T2 is a well-defined elementary contractile structure which is the simplest type of motor apparatus and is very convenient for conducting structural and physicochemical investigations.

T2 phage is more properly called Enterobacteria phage T2. It is a virulent bacteriophage which infects Escherichia coli bacteria . It contains linear double-stranded DNA , and is covered by a protective protein coat.

Escherichia coli bacteriophages T2, T4, and T6 encode a DNA topo II that is different from the host enzymes. These enzymes relax superhelical DNA in an ATP-dependent reaction, and they are incapable of introducing superhelical turns into the DNA.

Synthetic biology techniques allow the generation of various chimera phages in the T2, T4, and T7 families, each of which targets different bacterial receptors for synergistic therapy and thus delay the emergence of phage-resistant clones .

This chapter discusses the life cycle of T2 bacteriophage, which is one of a somewhat an arbitrary family of phages capable of attacking Escherichia coli, strain B. The physical properties, morphology, biochemical make-up, and life cycles of these phages are well known.

Bacteriophages “bacteria-eater” are infectious agents that replicate as obligate intracellular parasites in bacteria with high selectivity. They are the powerful regulators of bacterial populations in natural ecosystems and are found in the soils, plants, rivers, and …

2024年12月17日 · Understanding the differences in viral structure between T2 and T4 bacteriophages provides valuable insights into their mechanisms of infection, replication, and evolution.

The T2 phage is typical one common group of phages. The body of the virus, called a capsid, is a complex structure with a head containing DNA and a tail apparatus that attaches to receptors on the surface of the bacterial host.