Measurement of natural variations in the abundances of stable isotopes of the same element is normally referred to as stable isotope analysis. This field is of interest because the differences in mass between different isotopes leads to isotope fractionation, causing measurable effects on the isotopic composition of samples, characteristic of ...

The traditional ‘stable isotope ratio mass spectrometry’ approach for light element fractionation studies (H, C, N, O, S) uses gas-phase sample introduction, electron impact ionization, and analysis with specialized magnetic sector instruments.

A stable isotope ratio mass spectrometer consists of an inlet system, an ion source, an analyzer for ion separation, and a detector for ion registration. The inlet system is designed to handle pure gases, principally CO2, N2, H2, and SO2 but also others …

2024年4月23日 · In the first one, we provide a step-by-step beginner’s guide for performing multi-elemental, intramolecular and site-specific stable isotope analysis in unlabeled polar solutes by direct...

2024年9月12日 · SIMSL is equipped for the stable isotopic (‰) and elemental (%) composition analysis of carbon (C) and nitrogen (N), in organic and inorganic phases (solids, liquids and gases) as well as oxygen (O) and hydrogen (H) in water samples.

2024年11月1日 · The analysis of stable isotope ratios (SIRA) of the bioelements through stable isotope ratio mass spectrometry (IRMS) in organic molecules, both of natural and synthetic origin, is a powerful technique to obtain relevant information about their provenance and the steps involved in their biological or chemical synthesis.

Measurements of stable isotope ratios in soils and plant samples are used to reconstruct past climates and vegetation, evaluate physiological responses of wild and domesticated plants (and animals), characterize energy and material transfers and transformations among plant, animal, and microbial components of ecosystems, and understand ...

In this tutorial, the authors explain how naturally occurring stable isotopes are contributing to experimentally determined mass spectra and how this information can be exploited in quantitative experiments, structural elucidation studies and tracer ...

2015年9月10日 · This document describes the different stable isotope labelling methods which incorporate metabolic labelling in live cells, ICP-MS based detection and post-harvest chemical label tagging for protein quantification, in addition to summarising their pros and cons.

Isotope ratio mass spectrometers are designed to minimise these effects. For example, they are usually operated in flat-topped peak mode (Bluck and Volmer 2008), which minimises the effect of mass drift. Secondly, they use Faraday buckets rather than electron multipliers as detectors because of the greater stability of the former.