Small interfering RNA (siRNA), sometimes known as short interfering RNA or silencing RNA, is a class of double-stranded non-coding RNA molecules, typically 20–24 base pairs in length, similar to microRNA (miRNA), and operating within the RNA interference (RNAi) pathway.

One of the most important advances in biology has been the discovery that siRNA (small interfering RNA) is able to regulate the expression of genes, by a phenomenon known as RNAi (RNA interference).

Small interfering RNA (siRNA) delivery by nanocarriers has been identified as a promising strategy in the study and treatment of cancer. Short nucleotide sequences are synthesized exogenously to create siRNA, which triggers RNA interference (RNAi) ...

2019年9月4日 · The siRNA is also known as small interfering ribonucleic acid or silencing RNA and is a molecule that prevents gene expression. This means it silence genes. The entire process of gene silencing through the siRNA is called a mechanism of RNA interference or …

Post-transcriptional gene silencing targets and degrades mRNA transcripts, silencing the expression of specific genes. RNA interference technology, using synthetic structurally well-defined short double-stranded RNA (small interfering …

Small interfering RNA (siRNA), also known as short interfering RNA or silencing RNA, is a kind of non-coding double-stranded RNA containing 21-22 nucleotide base pairs that interfere with the expression of particular genes and mRNA translation by …

Small interfering RNA (siRNA), also known as short interfering RNA or silencing RNA, is a class of double-stranded RNA molecules (20–25 bp length) and interferes with the expression of specific genes with complementary nucleotide sequences. RNAi has been a promising therapeutic approach for diseases with aberrant protein production.

2024年5月30日 · What is Small Interfering RNA (siRNA)? Small interfering RNA (siRNA), also known as short interfering RNA or silencing RNA, is a type of double-stranded RNA molecules that function within the RNA interference (RNAi) pathway.

2020年6月19日 · RNA interference (RNAi) is an ancient biological mechanism used to defend against external invasion. It theoretically can silence any disease-related genes in a sequence-specific manner, making...

RNA interference starts with a long double-stranded RNA, such as the ones formed as viruses replicate. The protein dicer, shown here at the top in blue from PDB entry 2ffl , cuts this RNA into small, distinctive pieces called small interfering RNA …