2023年6月26日 · In the microgranular variant (20% to 30%), pellets and Auer rods are less prominent, and the nucleus has a characteristic bilobed, folded appearance. Other less …

› Classic Immunophenotype: CD34- CD117+ HLA-DR- CD13+ CD33+ (they may have immunophenotypic aberrancies such as gain of CD56, etc.) › Cartoon Image: Click and drag …

Abnormal promyelocyte from a patient with acute promyelocytic leukaemia (APML), showing numerous Auer rods and azurophilic granules, which almost completely obscure the cellular …

2011年10月5日 · Acute promyelocytic leukemia: blood smear with many large promyelocytes with Auer rods. These cells are characterized by a phenotype CD19 +, CD117 +, MPO +, CD13 + …

2017年5月30日 · Leukemic promyelocyte in the peripheral blood demonstrating multiple clusters of Auer rods in the cytoplasm. Such leukemic promyelocytes are often referred to as "Faggot" …

Acute promyelocytic leukemia (APL) falls into the latter category. It is composed of malignant promyelocytes, which often have a distinctive appearance. But the really characteristic finding …

Auer rods (or Auer bodies) are large, crystalline cytoplasmic inclusion bodies sometimes observed in myeloid blast cells during acute myeloid leukemia, acute promyelocytic leukemia, high …

We hypothesize a novel origin for Auer body development in promyeloblasts of APL, namely that they originate from peroxidase-positive and expanded rER cisternae, and that primary …

2023年6月7日 · Myeloid elements: Predominance of atypical promyelocytes in bone marrow. The neoplastic promyelocytes are large cells and most of them are heavily granulated. Many …

In the microgranular variant, the abnormal promyelocyte cells demonstrate a lack of granulation but often have abnormal bi-lobed nuclei. Cells may contain characteristic multiple or bundles …