
Prostaglandin E2 - Wikipedia
Prostaglandin E2 (PGE2), also known as dinoprostone, is a naturally occurring prostaglandin with oxytocic properties that is used as a medication. [2][3][4] Dinoprostone is used in labor …
Role of prostaglandin E2 in tissue repair and regeneration - PMC
Prostaglandin E2 (PGE2), which involves diverse physiological processes via E-type prostanoid (EP) receptor family, favors the regeneration of various organ systems following injury for its …
Prostaglandin E2 (Dinoprostone) - StatPearls - NCBI Bookshelf
2023年6月5日 · Prostaglandin E2 (PGE2), also known by the name dinoprostone, is a naturally occurring compound involved in promoting labor, though it is also present in the inflammatory …
Regulation of Immune Responses by Prostaglandin E2 - PMC
Prostaglandin E 2 (PGE 2), an essential homeostatic factor, is also a key mediator of immunopathology in chronic infections and cancer. The impact of PGE 2 reflects the balance …
Prostaglandin E2 synthesis and secretion: the role of PGE2
2020年3月15日 · Prostaglandin E2 (PGE2) is a principal mediator of inflammation in diseases such as rheumatoid arthritis and osteoarthritis. Nonsteroidal anti-inflammatory medications …
Multifaceted roles of PGE2 in inflammation and cancer - PMC
Prostaglandin E 2 (PGE 2) is a bioactive lipid that elicits a wide range of biological effects associated with inflammation and cancer. PGE 2 exerts diverse effects on cell proliferation, …
PGE2 limits effector expansion of tumour-infiltrating stem
2024年4月24日 · Here we demonstrate that tumour-derived prostaglandin E2 (PGE 2) restricts the proliferative expansion and effector differentiation of TCF1 + CD8 + T cells within tumours, …
Prostaglandin E2-EP2/EP4 signaling induces immunosuppression …
2024年11月1日 · While prostaglandin E 2 (PGE 2) is produced in human tumor microenvironment (TME), its role therein remains poorly understood. Here, we examine this issue by comparative …
Prostaglandin E2-induced inflammation: Relevance of ... - PubMed
Prostaglandin E2 (PGE2) is one of the most typical lipid mediators produced from arachidonic acid (AA) by cyclooxygenase (COX) as the rate-limiting enzyme, and acts on four kinds of …
Prostaglandin E2 constrains systemic inflammation through an innate ...
2016年3月18日 · We observed that prostaglandin E 2 (PGE 2), through its receptor EP4, is down-regulated in human systemic inflammatory disease. Mice with reduced PGE 2 synthesis …