GABA transporter - Wikipedia
GABA transporters in the plasma membrane help in regulating the concentration of GABA in the extracellular matrix by reabsorbing the transmitter and clearing the synapse. They transiently …
GABA transport cycle: beyond a GAT feeling - Nature
2023年7月3日 · Four GABA transporter (GAT) subtypes, GAT1, GAT2, GAT3 and betaine/GABA transporter 1 (BGT1), are the key regulators of inhibitory neurotransmission through cellular …
Structure, function, and plasticity of GABA transporters
2014年6月16日 · Here we review the current knowledge on the structural and functional properties of GABA transporters and highlight the molecular mechanisms that alter the …
Structural basis of GABA reuptake inhibition - Nature
2022年6月8日 · γ-Aminobutyric acid (GABA) transporter 1 (GAT1) 1 regulates neuronal excitation of the central nervous system by clearing the synaptic cleft of the inhibitory neurotransmitter …
Molecular basis for substrate recognition and transport of human GABA …
2023年7月3日 · GAT1, which is mainly expressed in the presynaptic terminals of axons, is a potential drug target of neurological disorders due to its essential role in GABA transport. Here …
Localization and Function of GABA Transporters GAT-1 and GAT-3 …
GABA transporter type 1 and 3 (GAT-1 and GAT-3, respectively) are the two main subtypes of GATs responsible for the regulation of extracellular GABA levels in the central nervous system.
GABA Transporter - an overview | ScienceDirect Topics
GABA Transporters, in the context of neuroscience, refer to electrogenic transporters that facilitate the symport of GABA along with Na+ and Cl- ions across the plasma membranes of …
GABA Transporter - an overview | ScienceDirect Topics
The GABA transporter is a symport carrier that couples the transport of two Na+, one Cl−, and one GABA molecule into the cell. From: Foundations of Anesthesia (Second Edition), 2006
Regulation of Glutamate, GABA and Dopamine Transporter …
Here we discuss recent advances in the mechanisms that control the cell membrane trafficking and biophysical properties of transporters for the excitatory, inhibitory and modulatory …
Localization and Function of GABA Transporters GAT-1 and GAT-3 …
2011年7月28日 · GABA transporter type 1 and 3 (GAT-1 and GAT-3, respectively) are the two main subtypes of GATs responsible for the regulation of extracellular GABA levels in the …
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