Introduction. Intraocular pressure (IOP) is the most important modifiable risk factor for development and progression of primary open-angle glaucoma (POAG).1 Lowering IOP remains the only proven treatment to delay conversion of ocular hypertension (OHT) to POAG,2 and to slow disease progression in established glaucoma.3–5 Topical IOP-lowering medication is the most common initial therapeutic ...

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The British Journal of Ophthalmology (BJO) is an international peer-reviewed journal for ophthalmologists and visual science specialists. BJO publishes clinical investigations, clinical observations, and clinically relevant laboratory investigations related to ophthalmology.

British Journal of Ophthalmology is pleased to present a topic collection on Generative AI in Ophthalmology. The field of ophthalmology has witnessed remarkable advancements in recent years, and the emergence of generative artificial intelligence (AI) techniques has further revolutionized research and clinical applications.

British Journal of Ophthalmology is an international peer-reviewed journal for ophthalmologists and visual science specialists that publishes clinical investigations, clinical observations, and clinically relevant laboratory investigations related to ophthalmology. Main features include articles on both clinical and laboratory sciences, up-to-date major reviews, editorials, education articles ...

Background/aims Age-related macular degeneration (AMD) and cancer may share similar risk factors, indicating possible common pathogenic pathways. We aimed to describe the site-specific cancer risk based on the relationship of AMD with visual disability (VD) status. Methods This was a population-based cohort study using data from the Korean National Health Insurance Service database (2009 ...

Stargardt macular dystrophy (Stargardt disease; STGD1; OMIM 248200) is the most prevalent inherited macular dystrophy. STGD1 is an autosomal recessive disorder caused by multiple pathogenic sequence variants in the large ABCA4 gene (OMIM 601691). Major advances in understanding both the clinical and molecular features, as well as the underlying pathophysiology, have culminated in many ...

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The management and outcome of retinal disorders was revolutionised with the advent of ocular anti-vascular endothelial growth factor (VEGF) therapies including US Food and Drug Administration (FDA)-approved ranibizumab (Lucentis; Genentech, South San Francisco, CA, USA) and aflibercept (Eylea; Regeneron, Tarrytown, NY, USA) and off-label bevacizumab (Avastin; Genentech). With the widespread ...

Purpose To investigate the long-term effect of orthokeratology (ortho-k) on the choroidal thickness and choroidal contour in myopic children. Methods Subjects were from a conducted 2-year randomised clinical trial. Children (n=80) aged 8–12 years with spherical equivalent refraction of −1.00 to −6.00D were randomly assigned to the control group (n=40) and ortho-k group (n=40).