2017年7月25日 · The function of telomerase is to add more nucleotides to the telomeres, regenerating these protective “caps” and helping the vital regions of our DNA to avoid …

2022年12月11日 · Function. The main functions of a telomere are to maintain chromosomal stability and prevent chromosomal degradation. Additionally, telomeres protect the ends of the …

Telomerase is a reverse transcriptase enzyme that carries its own RNA molecule (e.g., with the sequence 3′- C CC A A U CCC-5′ in Trypanosoma brucei) [3] which is used as a template …

Telomerase is the enzyme responsible for maintenance of the length of telomeres by addition of guanine-rich repetitive sequences. Telomerase activity is exhibited in gametes and stem and …

2024年12月23日 · Telomerase (terminal transferase) is a ribonucleoprotein enzyme that extends telomeres, the repetitive nucleotide sequences at the ends of eukaryotic chromosomes. …

In this review, we outline the pathways controlling the expression, assembly, and function telomerase, as well as discuss the telomeric and extratelomeric mechanisms connecting …

In mammals, maintenance of the linear chromosome ends (or telomeres) involves faithful replication of genetic materials and protection against DNA damage signals, to ensure …

Telomeres are essential nucleoprotein structures that define the terminal segments of linear chromosomes. In eukaryotes, telomeres are essential for genome stability, functioning to …

telomerase, enzyme that influences cell life span by adding organic compounds known as nucleotides to telomeres, segments of DNA located at the ends of chromosomes. Telomeres …

2020年4月2日 · In this Review, we discuss the transcriptional regulation of human TERT, hTR processing, assembly of the telomerase complex, the cellular localization of telomerase and its …