Treatment with DNX-2401 led to significant remission and long-term survival in recurrent high-grade gliomas, possibly due to the direct oncolytic effect of the virus, which triggered an …

2023年5月29日 · Glioma is the most prevalent type of primary brain tumor, and glioblastoma multiforme (GBM) is the highest and most deadly type of primary central nervous system …

Fortunately, nano-delivery systems have demonstrated unprecedented capabilities in diagnosing and treating gliomas in recent years. They have been modified and surface modified to …

2024年6月11日 · Moreover, the functionalized nanosystem significantly extended the median survival time compared to that of the control groups. The study showed that the nanoplatform …

With the aid of radiation, CXCR4 blockade SPNP profoundly prolonged the survival of mice with OL61 glioma (Figure 11d,e), and effectively prevented tumor rechallenge (Figure 11f), which …

2024年11月29日 · Overall, we report an effective drug delivery nanoplatform across the BBB for an enhanced therapy of glioma. Glioma is the most fatal intracranial malignancy nowadays, …

2021年12月2日 · Moreover, the median age at first diagnosis is 65 years and the 12-month survival is poor with around 42.8% (2). Standard therapy includes maximum safe resection …

2024年4月15日 · As primary intracranial tumors of the central nervous system (CNS), gliomas pose formidable challenges in the field of oncology due to their aggressiveness, poor …

In recent years, the treatment of glioma has developed rapidly, but the overall survival of glioma patients has not significantly improved. Due to the presence of the blood–brain barrier and …

2024年4月17日 · These nano-systems have demonstrated exceptional therapeutic effects in the treatment of glioma by various responsive ways, including temperature-response, pH …