The presence of PEG on the surface of the liposomal carrier has been shown to extend blood-circulation time while reducing mononuclear phagocyte system uptake (stealth liposomes). …

This review focuses on stealth technology and summarizes pre-clinical and clinical data relating to the principal liposome formulations; it also discusses emerging trends of this promising …

modification of the terminal PEG molecule, stealth liposomes can be actively targeted with monoclonal antibodies or ligands. This review focuses on stealth technology and summarizes

The goal of stealth technologies is to overcome the effects of the surface properties of the liposomes without pharmacologically affecting the clearance mechanisms of the body. After …

2011年5月1日 · Further, by synthetic modification of the terminal PEG molecule, stealth liposome can be actively targeted with monoclonal antibodies or legends. This review focuses on stealth …

1997年3月17日 · 'Due to their invisibility to the body's defence system sterically stabilized liposomes are often called also Stealth® liposomes (a registered trademark name of Sequus …

2006年2月1日 · The presence of PEG on the surface of the liposomal carrier has been shown to extend blood-circulation time while reducing mononuclear phagocyte system uptake (stealth …

2024年5月7日 · Stealth liposomes are extensively studied for their improved circulation time and better pharmacokinetic profile in cancer treatment. The steric hindrance of the stealth …

2003年11月1日 · Following intravenous injection, liposomes and nanoparticles are cleared rapidly from the blood (usually within minutes) by elements of the RES, particularly the hepatic …

2022年5月1日 · PEGylated liposomes are denoted as stealth liposomes [97, 98]. Doxil® was the first successful pegylated liposome-based product [99]. Stealth stabilized liposomes showed …