In smooth muscle, there is a single gene (MYH11 [9]) that codes for the heavy chains myosin II, but there are splice variants of this gene that result in four distinct isoforms. [8] Also, smooth …

2023年8月14日 · Smooth muscle cytoplasm contains large amounts of actin and myosin. Actin and myosin act as the main proteins involved in muscle contraction. Actin filaments attach to …

Both smooth muscle (SM) and non-muscle (NM) myosin II are expressed in hollow organs such as the bladder and uterus, but their respective roles in contraction and corresponding …

Smooth muscle myosin has three different regions that vary to generate different isoforms: (1) an alternative insertion within the myosin head; (2) two possible essential light chains; and (3) an …

Individual SM cells may express one or more of multiple myosin II isoforms that differ in myosin heavy chain (MHC) and myosin light chain (MLC) subunits. Although much has been learned, …

1998年3月1日 · The data revealed that smooth muscle myosin may have the capacity to generate 3–4 times the average force per myosin head than does skeletal muscle myosin. These data, …

Smooth muscle generates as much force per cross sectional area of muscle as skeletal muscle with only one-fifth the myosin content. Although this apparent difference could be explained at …

2004年12月12日 · Fluorescent transients reporting release of an ADP analogue 3'-deac-edaADP were significantly faster in phasic than in tonic smooth muscles. Thiophosphorylation of …

The smooth muscle isoform of myosin light chain kinase (MLCK) is a Ca 2+ -calmodulin-activated kinase that is found in many tissues. It is particularly important for regulating smooth muscle …

2007年10月5日 · Using negative stain electron microscopy of individual folded myosin molecules from turkey gizzard smooth muscle, we show that they are more compact than previously …