A biodegradable polylactic acid (PLA)/poly(glycolide-co-lactide) copolymer (PLGA) membrane with polyglycolic acid (PGA) mesh was prepared to aid the effective regeneration of defective periodontal tissues.

In this study, GTR membrane (PLA/ PGA membrane) was used as a scaffold for delivery of MSCs. The test group in the study showed mean recession defect coverage of 66.26% with 45.23 % of teeth showed complete root coverage, the mean PPD reduction in test group was 0.35±0.37mm and mean CAL gain in test group was 1.78±1.1mm at 6 months.

Hybrid membrane fusion-disguised PLGA NPs, instead of a mixture of single membrane-coated NPs, recapitulated the functions of source cells and exhibited much better behavior than their counterpart. Researchers have been inspired to customize different hybrid membrane groups according to the diverse disease pathology.

2023年9月1日 · In this paper, a cell membrane-encapsulated biomimetic drug delivery system (PM/RM@PLGA@P/R) based on ginsenoside Rg1 and PFH was successfully constructed. Where the nanoparticles were coated with the mixed membrane of red blood cells (to avoid the immune system and thus increasing the drug’s accumulation in the thrombus region instead of the ...

2021年2月1日 · Poly (glutamic acid) (PGA) is an amino acid biopolymer that has recently attracted attention due to its biocompatibility, non-immunogenicity, and biodegradability. PGA and its composites have been studied to improve their function as medical materials. This review briefly introduces chemically and microbiologically synthesized PGA.

2019年7月1日 · The in vitro cell culture study showed favorable biocompatibility of nanofibers. The in vivo animal experiment showed that PLA/γ-PGA core-shell nanofiber membrane was conducive to wound repair, where more than 90% re-epithelialization was observed. It suggested a promising and dependable material for tissue engineering and wound healing.

Stem cells in combination with bioresorbable PLA/PGA membrane was effective for root coverage resulted in a significant reduction in gingival recession, greater gain in CAL and WKG. Stem cells in combination with bioresorbable PLA/PGA membrane …

The emerging cell membrane (CM)-camouflaged poly(lactide-co-glycolide) (PLGA) nanoparticles (NPs) (CM@PLGA NPs) have witnessed tremendous developments since coming to the limelight. Donning a novel membrane coat on traditional PLGA carriers enables ...

Another research group evaluated the potential of human umbilical mesenchymal stem cells in combination with PLA/PGA membrane (BioMesh-S®, Samyang Corporation) in the treatment of multiple ...

The emerging cell membrane (CM)-camouflaged poly(lactide-co-glycolide) (PLGA) nanoparticles (NPs) (CM@PLGA NPs) have witnessed tremendous developments since coming to the limelight. Donning a novel membrane coat on traditional PLGA carriers enables combining the strengths of PLGA with cell-like beha …