2017年7月25日 · Polymer nanoparticles made of polyethylene (PE), polypropylene (PP) and polystyrene with size up to 7 nm enter easily POPC lipid membranes, localizing to the …

We find that PE, PP and PS can passively penetrate the hydrophobic core of model lipid membranes, and, despite their similar degree of hydrophobicity, alter membrane physical …

2013年10月1日 · Overview of the different hybrid vesicular structures that can be obtained according to the molar composition (polymer/lipid molar ratio) and thermodynamic phase of …

In this study, we focused on how the hydrophilic blocks impact the vesicle’s morphology. Therefore, we developed hybrid lipid/polymer vesicle systems with lipid 1,2-dioleoyl- sn …

2021年11月8日 · In particular, polymer hydrophobicity is a property of interest, with growing evidence demonstrating the significant impact that hydrophobic interactions with lipid …

2022年1月1日 · Lipid polymer hybrid nanoparticles (LPHN) are novel systems which are potentially emerging in the era of nano-medicine. They are core-shell nanostructures which …

2017年7月25日 · Our results show that different hydrophobic polymers have major effects on the properties of lipid membranes, calling for further investigations on model systems and cell …

common hydrophobic group used in SMA polymer nanodiscs is the styrene moiety. It is known that. the formation of nanodiscs. In this study, we employed a simple and robust modification …

Polymers designed to interact with lipids often mimic the structure and behavior of natural lipid molecules. The polymer chain typically includes a hydrophobic (water-repellent) segment …

We report the engineering of a novel lipid-polymer hybrid nanoparticle (NP) as a robust drug delivery platform, with high drug encapsulation yield, tunable and sustained drug release …