I graduated from the University of Tokyo School of Medicine and became a Humboldt fellow in the Max-Planck Institute, Germany. After coming back to Japan, I was an Assistant and then Associate Professor of the Physiology Department of the University of Tokyo, and promoted to Professor of the National Institute of Physiological Sciences, Okazaki.

2024年12月16日 · Haruo Kasai is assigned as a project professor in WPI-IRCN. Our lab is recruiting graduate students and postdocs. Dr. Haruo Kasai receives the Imperial Prize and the Japan Academy Prize. The last lecture of Prof. Haruo Kasai in Faculty of Medicine will be delivered at Tetsumon-kodo and Zoom.

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大脳のシナプスの運動性は心の成立や精神疾患に深く関係することを見出し、更なる謎の解明を進めています。 私たちの研究室は、脳科学において学習と記憶のメカニズムに焦点を当てています。 私たちは、大脳の樹状突起スパインがこれらのプロセスで重要な役割を果たしていることに注目しています。 樹状突起は、神経細胞の間の接続を形成する興奮性シナプスの上に存在する特徴的な構造です。 私たちは、光学技術を使ってシナプスの操作を行い、樹状突起スパイン …

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我々の研究室では光学的・分子生物学的な手法を運用して脳機能のシナプスや分子基盤を明らかにする研究を世界的に展開してきた。 それらの手法を用いてシナプス結合の増強時にシナプスが増大運動を起こすことを、海馬、大脳新皮質や基底核で明らかにしてきた。 シナプスの動的な挙動は神経修飾因子や向精神薬、そして依存性物質的の作用に深く関連する。 そこで、その動的特性を利用した光学的分子プローブを作成して、学習やその他の認知機能やその異常を解明す …

Haruo Kasai's 166 research works with 14,797 citations and 17,910 reads, including: Unraveling the mysteries of dendritic spine dynamics: Five key principles shaping memory and...

We found the dendritic spine enlarges with a strength of muscle tension, and pushes the presynaptic terminal to promote exocytosis (PREST). This likely is a cellular basis of short-term and working-like memories, because PREST occurs rapidly, synapse specific, and …

On March 14, 2022, Prof. Haruo Kasai, IRCN Principal Investigator and Professor in the School of Medicine at The University of Tokyo, received the Imperial Prize and the Japan Academy Prize, which are bestowed upon academic scholars who have achieved notable research landmarks and authored particularly outstanding academic papers or books.

Haruo Kasai practices in Tokyo, Japan. His top areas of expertise are Oppenheim Dystonia and X-Linked Dystonia-Parkinsonism. His clinical research consists of co-authoring 59 peer reviewed articles in the past 15 years.