2021年11月25日 · Recent research reveals that cross-talk along the gut-brain axis regulates inflammatory nociception, inflammatory responses, and immune homeostasis. Here, we discuss molecular and cellular mechanisms involved in the signaling of …

Recent research reveals that cross-talk along the gut-brain axis regulates inflammatory nociception, inflammatory responses, and immune homeostasis. Here, we discuss molecular and cellular mechanisms involved in the signaling of inflammation across the gut-brain axis.

2021年11月26日 · Recent research reveals that cross-talk along the gut-brain axis regulates inflammatory nociception, inflammatory responses, and immune homeostasis. Here, we discuss molecular and cellular mechanisms involved in the signaling of …

A healthy gut with diverse microbes is vital for normal brain functions and emotional behaviors. In addition, the CNS controls most aspects of the GI physiology. The molecular interaction between the gut/microbiome and CNS is complex and bidirectional, ensuring the maintenance of gut homeostasis and proper digestion.

2022年1月10日 · Using a model of inflammatory bowel disease (in which a chemical called DSS is given to mice in their drinking water to induce intestinal inflammation), the authors investigated whether...

The gut–brain axis is a bidirectional communication system driven by neural, hormonal, metabolic, immunological, and microbial signals. Signaling events from the gut can modulate brain function and recent evidence suggests that the gut–brain axis ...

In this comprehensive review, we summarize the role of the brain-gut axis in the psychological functioning of patients with IBD, and discuss current preclinical and clinical data on the topic and therapeutic strategies potentially useful for the clinical management of these patients.

2024年7月15日 · Recent studies suggest that gut microbiota can modulate neuroinflammation, affecting microglial activation and CNS health [1, 2]. The use of synbiotics, combining probiotics and prebiotics, show promise in restoring gut microbiota …

2023年11月7日 · Gut inflammation is thought to modify brain activity and behaviour via modulation of the gut-brain axis. However, how relapsing and remitting exposure to peripheral inflammation over the natural history of inflammatory bowel disease (IBD) contributes to altered brain dynamics is poorly understood.

2020年10月22日 · In this Review, we describe the state of the art in gut microbiota–brain research, evidence for involvement of the gut microbiota in disorders of the brain and intriguing opportunities...