We can distinguish four main virulence classes of E. coli pathotypes: colonization, fitness, toxins, and effectors; each consists of several specific virulence factors with a definite function and activity .

2019年2月21日 · Uropathogenic E. coli have many virulence factors, i.e. adhesins, toxins (e.g. alpha-hemolysin, cytotoxic necrotizing factor 1, autotransporter toxins), iron/heme-acquisition systems, and iron ion transport. P, S and type 1 fimbriae are responsible, among others, for adhesion to epithelial cells of intestines, kidneys, or lower urinary tract ...

Virulence factors of E. coli can affect a wide range of eukaryotic cellular processes, including cell signalling, ion secretion, protein synthesis, mitosis, cytoskeletal function and...

2024年10月20日 · Understanding the virulence factors of pathogenic E. coli is important due to its impact on human health, causing diseases like urinary tract infections and severe gastrointestinal illnesses. The study of these virulence factors reveals how E. coli interacts with host cells, leading to disease progression.

2013年3月15日 · Since the topic of the ECMIS congress is the interaction between E. coli and the mucosal immune system, the purpose of this manuscript is to give an overview of the most important virulence-associated properties of E. coli that can directly interact with the epithelial cells, i.e. adherence factors and “exotoxins”. The adherence to the ...

2009年12月7日 · Pathogenic E. coli are diverse in their gene sets. Many virulence factors are maintained on a virulence plasmid and were acquired through horizontal gene transfer. Others were integrated...

2021年9月14日 · This review summarizes new developments in our understanding of diverse virulence factors associated with encoding genes used by different pathotypes of enteric pathogenic E. coli to cause intestinal and extraintestinal diseases in humans.

2021年9月14日 · This review summarizes new developments in our understanding of diverse virulence factors associated with encoding genes used by different pathotypes of enteric pathogenic E. coli to cause...

2013年3月15日 · At least three different general classes of E. coli adhesins can be defined: different appendices like fimbriae, fibrillae and curli, the afimbrial family (Afa), and specific outer membrane proteins (OMPs) like the intimin (Kaper et al., 2004, Mainil, 2005a).

2020年3月29日 · Certain properties of EPEC such as virulence factor, antigenic property, self-formation of clusters, and restricted attachment to epithelial cells are due to adherence factor plasmid (pEAF), which encodes bundle forming pili (Trabulsi et al. 2002).