In this review, we discuss the importance of capsaicin to the current understanding of neuronal modulation of pain and explore the mechanisms of capsaicin-induced pain. We will focus on …

2023年5月23日 · Capsaicin is a chili pepper extract, genus Capsicum, with analgesic properties. Since its discovery, it is used as a homeopathic remedy to treat burning pain using the concept …

Capsaicin exerts analgesic, antioxidant, cardioprotective, anticancer and thermogenic effects, and it can promote weight loss (3). Some of these effects are mediated by the receptor called …

Capsaicin is the pungent ingredient of chili peppers and is approved as a topical treatment of neuropathic pain. The analgesia lasts for several months after a single treatment. Capsaicin …

2021年4月1日 · Recent studies have shown that capsaicin-induced Ca2+/calpain-mediated ablation of axonal terminals is necessary to produce long-lasting analgesia in a mouse model …

2020年6月19日 · Capsaicin, which is found in chili peppers, has been used as a topical agent to relieve pain. 3 It is a transient receptor potential vanilloid 1 receptor (TRPV1) agonist; it binds …

2013年11月15日 · There have been numerous clinical trials which studied the analgesic effect of capsaicin in humans (Anon, 2013). A recently published prospective observational study …

2008年10月1日 · Capsaicin is thought to produce analgesia by depleting substance P in small fibre nociceptor neurons on which Transient Receptor Potential action channel (subfamily V), …

2016年11月1日 · Capsaicin is the pungent ingredient of chili peppers and is approved as a topical treatment of neuropathic pain. The analgesia lasts for several months after a single treatment. …

The analgesic, anti-inflammatory or apoptotic effects of capsaicin show promising results in arthritis, neuropathic pain, gastrointestinal disorders or cancer, since evidence demonstrates …