Articular cartilage is adapted to be able to perceive and respond to mechanical load. Indeed, physiological loads are essential to maintain cartilage thickness in a healthy joint and …

Articular cartilage consists of one cell type, articular chondrocytes, and the extracellular matrix provided by these cells. The matrix is comprised primarily of collagen, proteoglycans, and …

2020年11月24日 · The articular surface shows advanced osteoarthritic changes characterized by fissuring and fragmentation of the articular cartilage, chondrocyte proliferation and …

2022年1月1日 · In the knee joint, articular cartilage provides biomechanical functions that are essential for locomotion, including load bearing (Maroudas, 1979), energy dissipation (Mow, …

2015年1月1日 · Articular cartilage injuries present a unique and challenging medical problem due to the tissue's lack of regenerative ability. The reduced vascularity, limited cell population, and …

2022年5月26日 · Articular cartilage lends itself well to investigating the function of the ECM. By volume, the ECM makes up around 90% of the tissue, with chondrocytes, the principal cell …

2023年7月30日 · Articular cartilage has a complex extracellular matrix (ECM) that provides it a defined architecture for its load-bearing properties. The complete understanding of ECM …

Cartilage extracellular matrix (ECM) is composed primarily of the network type II collagen (COLII) and an interlocking mesh of fibrous proteins and proteoglycans (PGs), hyaluronic acid (HA), …

Articular cartilage is a low-friction, load-bearing tissue located at joint surfaces. The extracellular matrix (ECM) of cartilage consists of a fibrous collagen network, which is pre-stressed by the …

2014年7月17日 · Cartilage matrix is a promising material for cartilage regeneration given the evidence supporting its chondroinductive character. The “raw materials” of cartilage matrix can …