Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Identified in 1986, [1] [2] activin enhances FSH biosynthesis and secretion, …

Activin A first binds to the type II activin receptors (ActIIRA or ActRIIB) on the member surface, and then recruits and phosphorylates type I activin receptors (ActRI). Activin A primarily signal …

激活素A(Activin A,ACV-A)是转化生长因子β超家族成员,是一种多功能细胞因子，多种免疫细胞可产生激活素A,如单核巨噬细胞、肥大细胞及部分淋巴细胞等。

Activin A is a member of the TGF-β superfamily of growth factors that plays a role in signaling through specific receptors to regulate bone metabolism, including bone resorption and …

Here, we provide an overview of the biology of activin-A and its signaling pathways, summarize recent studies pertinent to the role of activin-A in the modulation of inflammation and immunity, …

First identified as regulators of follicle-stimulating hormone secretion and erythropoiesis, activin and inhibin are involved in diverse processes during development and in terminally …

Activins are dimeric proteins consisting of β subunits which are connected by disulfide bonds. There are three different forms of activin, homodimeric activin A (βA – βA), and activin B (βB – …

激活素 （英語： Activin，亦成为 激活蛋白 或 活化素）与 抑制素 （英語： inhibin）是一种用于抑制 卵泡刺激素 分泌与组合的 梭氨酸 [1] 。 参与在 月经周期 的调节中。 抑制素属于 转化生长 …

2022年6月14日 · Activin A, a critical member of the transforming growth factor-β (TGF-β) superfamily, is a pluripotent factor involved in allergies, autoimmune diseases, cancers and …

Activin A has growth- and migration-promoting effects, contributes to immune evasion and cachexia and is associated with shorter survival in several cancer types. Targeting activin A …