Notably, Weis et al 11 showed that ketone-induced EC proliferation exhibits specificity for the cardiac tissue, ... Zhou T., Cheng X., He Y., et al. "Function and mechanism of histone beta-hydroxybutyrylation in health and disease". Front Immunol. 2022;13:981285. Google Scholar;

In our cohort, we have one female patient with 11β-hydroxylase (CYP11B1) deficiency (11-OHD) who was first admitted at the age of one year due to abnormal external genitalia. Laboratory results showed a renin level below 0.5 µIU/ml and a 17-OHP level greater than 60.6 nmol/L and no electrolyte disorder.

OBJECTIVE: to determine the 11-deoxycortisol (S) response and incidence of 11 beta-hydroxylase deficiency in hyperandrogenism. DESIGN: Hyperandrogenic women prospectively and consecutively ...

The initial biochemical workup revealed a profile indicating 11β-hydroxylase deficiency. However, genetic analysis did not show any evidence of CYP11B1 mutation. This patient manifested the florid signs of disrupted steroidogenesis brought by chronic use of electronic cigarette oil containing etomidate and propoxate/isopropoxate, which are ...

11-deoxycortisol is a steroid hormone. It can be produced in the adrenal glands. It is an intermediate in the synthesis of cortisol. 17-hydroxyprogesterone is converted to 11-deoxycortisol by the enzymes of 11β-hydroxylase (CYP11B1). The 11-deoxycortisol converts into cortisol.