Nystatin, one of the tetraene antifungal antibiotics, is very sensitive to light. Thus, when nystatin is exposed to natural daylight, it is photodegraded to products of lower biological activity. In this work, the photodegradation kinetics of nystatin was monitored by a …

2014年8月1日 · In this work, the photodegradation kinetics of nystatin was monitored by a UV-Vis spectrophotometry method. The absorbance spectra of the nystatin, exposed to a 366 nm UV lamp, were...

absorbance spectra of the nystatin, exposed to a 366 nm UV lamp, were recorded at different periods of time. By application of factor analysis to t

In the present study, biogenic selenium nanoparticles (SeNPs) have been prepared using Paenibacillus terreus and functionalized with nystatin (SeNP@PVP_Nystatin nanoconjugates) for inhibiting...

1977年1月1日 · From a comparison of the UV-absorption spectra of nystatin solutions in methanol/0.05% acetic acid and various aqueous buffer systems (pH 4.5, 6.8 and 9.01, Lampen et al.ll* concluded that the low extinction values typical for the aqueous media are likely to reflect that nystatin is present as micelles and is not in true solution.

2013年5月13日 · The UV spectrum of nystatin demonstrates three main local maxima at 290, 306 and 318 nm which are only reliable at constant molecular state (Cleary et al., 2003). The micellar structure of the polyene nystatin can lead to differences in the UV spectrum (Travkin et al., 1981).

It was pointed out that nystatin should not be storage under ultraviolet irradiation, because of decrease its antioxidative interactions. This studies confirmed usefulness of EPR spectroscopy and UV-Vis spectrophotometry to determine of the antioxidant character of drugs.

Current analysis undertook physical and chemical analyses in two samples of commercial nystatin (NYS I and NYS II). Moisture (Karl Fischer), spectroscopic (IR, UV and fluorescence) and thermal analyses (TGA and DSC) were conducted. The moisture was respectively 9.2% and 8.8% for samples I and II.

Nystatin, one of the tetraene antifungal antibiotics, is very sensitive to light. Thus, when nystatin is exposed to natural daylight, it is photodegraded to products of lower biological activity. In this work, the photodegradation kinetics of nystatin was monitored by a …

2014年9月30日 · Some methods to quantitatively determine nystatin in pharmaceutical samples have been proposed (high performance liquid chromatography, ultraviolet absorption spectrophotometry) and they...