Bacterial artificial chromosome - Wikipedia
A bacterial artificial chromosome (BAC) is a DNA construct, based on a functional fertility plasmid (or F-plasmid), used for transforming and cloning in bacteria, usually E. coli. [1] [2] [3] F-plasmids play a crucial role because they contain partition genes that promote the even distribution of plasmids after bacterial cell division.
Bacterial Artificial Chromosome (BAC) - National Human …
3 天之前 · A bacterial artificial chromosome (BAC) is an engineered DNA molecule used to clone DNA sequences in bacterial cells (for example, E. coli). BACs are often used in connection with DNA sequencing. Segments of an organism's DNA, ranging from 100,000 to about 300,000 base pairs, can be inserted into BACs.
细菌人工染色体 - 百度百科
细菌人工染色体（Bacterial artificial chromosome，BAC）是指一种以F质粒（F-plasmid）为基础建构而成的细菌染色体克隆载体，常用来克隆150kb左右大小的DNA片段，最多可保存300kb个碱基对。
Human BAC Resource - National Center for Biotechnology Information
The Human BAC Resource provides genome-wide resource of large-insert clones that helps integrate cytogenetic, radiation-hybrid, linkage, and sequence maps of the human genome.
General information on each BAC (Bacterial Artificial Chromosome) clone collection is provided in this section. The table below provides an overview of the different BAC Clone Collections, source, coverage, and vector information.
BAC/PAC 文库的构建-BAC文库的构建-丁香实验 - 丁香通研选
2024年5月13日 · bac是一种装载dna大片段的克隆载体系统，用于人、动物和植物基因组文库构建。bac具有插入片段较大(几千个碱基至350kb)、嵌合率低、遗传稳定性好、易于操作等优点。bac文库的构建是基因组较大的真核生物基因组研究的重要基础，可用于真核生物重要基因及全 ...
Bacterial Artificial Chromosome - an overview - ScienceDirect
Bacterial artificial chromosomes (BACs) are large genomic clones that are stably maintained in Escherichia coli. Because they are frequently large enough to contain an entire gene and its associated regulatory elements, BACs can serve as a source of …
基因组细菌人工染色体文库（BAC）的构建及应用 | Semantic Scholar
细菌人工染色体 (BAC)是一种承载DNA大片段的克隆载体系统,用于人、动物和植物基因组文库构建.BAC具有插入片断大、嵌合率低、遗传稳定性好、易于操作等优点.BAC文库的构建是基因组较大的真核生物基因组学研究的重要基础,可用于真核生物重要基因及全基因组物理作图、重要性状基因的图位克隆、基因结构及功能分析.本文主要综述了细菌人工染色体的构建与其鉴定,及其在物理图谱构建、图位克隆、转基因技术等研究上的应用. Sorry, we did not find any related papers. …
克隆库支持–入门 | Thermo Fisher Scientific - CN
BAC克隆为包含很大插入片段（>100 kb）的基因组克隆，可能包含几个基因，而cDNA克隆只包含一个开放读码框基因。BAC克隆适用于启动子及内含子／外显子分析，染色体定位及转基因小鼠制备。
Bacterial Artificial Chromosome - an overview - ScienceDirect
Bacterial artificial chromosomes (BACs) are plasmids used for cloning and stably maintaining large segments of foreign DNA in Escherichia coli. This is important in various types of analyses of mammalian and other genomes.
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