TIME (seconds) KEYDOWN HANDLER FIRING STATE ----- 0 Firing 0.25 Not firing 0.50 Not firing 0.75 Not firing 1 Firing 1.25 Firing 1.50 Firing 1.75 Firing 2 Firing opt_handler fires for every tick where ...

In meiosis, DNA double-strand break (DSB) formation by Spo11 initiates recombination and enables chromosome segregation. Numerous factors are required for Spo11 activity, and couple the DSB machinery ...

SMC complexes, such as condensin or cohesin, organize chromatin throughout the cell cycle by a process known as loop extrusion. SMC complexes reel in DNA, extruding and progressively growing DNA loops ...