Shenzhen Zhongge Biotechnology Co. Ltd. has synthesized serine/threonine-protein kinase ULK1 inhibitors reported to be useful for the treatment of cancer, lymphangioleiomyomatosis and tuberous ...

Scientists at Dongguk University and Korean Research Institute of Bioscience and Biotechnology have disclosed benzofuran compounds targeting heterogeneous nuclear ribonucleoprotein A2/B1 (hnRNPA2B1) ...

Tryptophan and lysine were therefore regarded as essential amino-acids, the list of which was afterwards extended to include histidine, threonine, valiae, phenylalanine, leucine, isoleucine and ...

Research Center for Analytical Sciences, Tianjin Key Laboratory of Biosensing and Molecular Recognition, College of Chemistry, Frontiers Science Center for New Organic Matter, Nankai University, ...

Abstract: Threonine proteases (TPs) are enzymes vital for several biological processes and diseases including Alzheimer's disease and cancer. Their potential to target and degrade proteins ...

Participants underwent polysomnography, amyloid β (Aβ) positron emission tomography, and plasma biomarker analysis, including phosphorylated tau at threonine 181 (p‐tau181), neurofilament ...

Tyrosine kinases (TKs) typically show strong binding affinity with a wide spectrum of type-II inhibitors while serine/threonine kinases (STKs) usually bind more weakly which we suggest here is due to ...