Translational Candidate An earlier, safer noninvasive prenatal screening test for β-thalassemia and sickle cell disease to identify candidates for prenatal stem cell therapy Area of Impact Our test is ...

Research Objective AAV9-Cas13 gene therapy for Angelman syndrome using a first-in-kind mechanism of action that will safely and permanently restore expression of endogenous UBE3A that is deficient in ...

Geron carried out a Phase 1 clinical trial to assess the safety and preliminary activity of escalating doses of human embryonic stem cell (hESC) derived oligodendrocyte progenitor cells for treatment… ...

众所周知，城市污染对肺部健康有不利影响。然而，城市污染如何影响不同的干细胞生态位区划仍然未知。这项研究旨在建立一个模拟复杂城市大气的肺损伤模型，以确定这些大气如何改变肺部的再生和干细胞活动。收集肺部，并分离出两种不同的肺泡细胞类型 ...

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The mission of California Institute for Regenerative Medicine (CIRM) is to accelerate world class science to deliver transformative regenerative medicine treatments in an equitable manner to a diverse ...

The DISC4 Pre-submission form is now closed. The mission of the California Institute for Regenerative Medicine (CIRM) is to accelerate world class science to deliver transformative regenerative ...

对于因对现有疗法产生耐药性而发生癌症转移的患者来说，治疗选择很少。该团队正在使用基因编辑技术来修改患者自身的 ...

South San Francisco, CA, March 27, 2025 — The California Institute for Regenerative Medicine (CIRM), one of the world’s largest institutions dedicated to regenerative medicine, approved new and ...

RNA 输入到哺乳动物线粒体被认为对于线粒体基因组的复制、转录和翻译至关重要，但控制这种输入的途径和因素却知之甚少。 此前，我们将多核苷酸磷酸化酶（PNPASE）（一种 3'→5' 核糖核酸外切酶和聚腺苷酸聚合酶）定位在线粒体膜间隙中，该位置缺乏常驻 RNA。

The statewide network is designed to overcome manufacturing bottlenecks that have delayed or stalled development and approval of regenerative medicines. “These awards are a critical first step in ...

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