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Proteolysis targeting chimera (PROTAC) technology has emerged as a powerful tool in drug discovery that enables targeted protein degradation through a unique bifunctional approach. This review ...
*The method used for pathogen detection is high-throughput sequencing. In conclusion, these findings underscore the importance of effective cockroach control across various environments to decrease ...
Objective: The goal of this study was to examine the prognostic performance of optical flow ratio (OFR) among patients with coronary artery disease (CAD) after percutaneous coronary intervention (PCI) ...
Silver nanoclusters (AgNCs) have emerged as highly adaptable nanomaterials with vast potential in theranostic applications, by integrating therapeutic and diagnostic capabilities within a single ...
Coronary heart disease (CHD), the most common cause of mortality globally, poses a formidable challenge to modern healthcare systems. Artificial intelligence (AI) is playing an increasingly important ...
Objectives: Meta-analysis was performed to evaluate the effect of staged revascularization with concomitant chronic total occlusion (CTO) in the non-infarct-associated artery (non-IRA) in patients ...
Diabetic cardiomyopathy (DCM), an independent diabetes complication, is characterized by abnormalities in myocardial structure, function, and metabolism, including diminished myocardial contractility, ...
*Cytotoxicities with IC 50 ≥ 5 μM are not listed. a ED 50 (in μM) was recorded. b GI 50 (in μM) was recorded. c From microbial transformation of gambogenic acid (isolated from G. hanburyi).
3.2 Anti-cancer activity of neocrytolepine and neocrytolepine derivatives against colorectal cancer Liver cancer is the fourth most common cancer globally. The occurrence of liver cancer is mainly ...
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Background: Although 2-methylbutyrylcarnitine (2MBC) has been associated with metabolic disorders and promotes thrombosis, its effect on atherosclerosis remains elusive. This study was aimed at ...
Background: Fenofibrate (FF) is a BCS class II compound whose poor solubility poses challenges in drug delivery and bioavailability. Solid self-micro emulsifying drug delivery systems (S-SMEDDS) have ...
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