Southbound Interstate 17 was closed in Phoenix after a wrong-way collision on Wednesday morning, authorities said.

For residents of this quaint tourist town on the northern edge of Napa Valley, the threat of wildfire is seldom out of mind.

Stepping into the lobby of the OdySea Aquarium in Scottsdale will soon feel like diving into nature through immersive ocean ...

Arizona State University will take part in a $142 million research project to understand why cancer resists treatment.

Football fans will recognize this week's guest on Amazing Arizonans: Super Bowl-winning Chicago Bears quarterback Jim McMahon.

Shares advanced Wednesday in Asia after U.S. stocks drifted closer to their records, while U.S. futures edged lower.

PHOENIX — Behavioral health provider Family Care Center has opened its fourth outpatient clinic in Arizona. The new Gilbert ...

Police in the suburbs of New York City have arrested who they described as a “ social media prankster” over viral videos in which he ...

KTAR News is joining the Arizona Cardinals as part of the fourth annual Civics Matters Arizona trip to Washington D.C.

Top Trump administration officials — fresh off touring one of the country's largest oil fields in the Alaska Arctic — ...

The U.N. Security Council scheduled a vote Wednesday on a resolution which demands “an immediate, unconditional and permanent ...

The officer injured in a shooting on Monday was the heartbeat of the Apache Junction Police Department, authorities said.