Shikonin is one of the primary active components extracted from the dried root ofZicao (Lithospermum erythrorhizon, Onosma paniculata, or Arnebia euchroma), a traditional Chinese herbal ...

Shikonin is one of the primary active components extracted from the dried root ofZicao (Lithospermum erythrorhizon, Onosma paniculata, or Arnebia euchroma), a traditional Chinese herbal medicine. S ...

Shikonin treated C6 glioma cells presented electron-lucent cytoplasm, loss of plasma membrane integrity and intact nuclear membrane in morphol. The increased ROS level caused by shikonin was ...

脂质体表面标记荧光，耦联多肽、甘露糖、蛋白、抗体和其他靶向分子；可以包裹核酸等pH敏感脂质体是一种能够在肿瘤等酸性微环境中响应性释放药物的智能递送系统，具有高效靶向和减少副作用的优点。通过pH敏感脂质体共载… ...

However, shikonin also has the common problem of anti-tumor drugs, that is, which has great toxic and side effects. Therefore, with the aim to make shikonin an antitumor drug for clinical, the ...

Shikonin has proven to be an efficient and less toxic potent bioactive phytoconstituent to maintain the quality of life for humans. However, various pharmacological applications, clinical studies and ...

Shikonin extracted from Lithospermum erythrorhizon was employed to develop pH-indicating biodegradable starch- and agar-based films using a solution casting method. The Fourier-transform infrared ...

Triple-negative breast cancer (TNBC) has an unfavorable prognosis attribute to its low differentiation, rapid proliferation and high distant metastasis rate. PI3K/Akt/mTOR as an intracellular ...