这篇综述聚焦肾脏疾病研究，阐述单细胞 RNA 测序（scRNA-seq）和空间转录组学（ST）技术在其中的应用。它们可解析细胞异质性，明确细胞亚群及相互作用，揭示疾病机制，为肾脏疾病诊疗和个性化医疗提供新思路。 肾脏疾病研究新视角：单细胞 RNA 测序与空间 ...

Recently, single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics have emerged as powerful tools to provide insights into the molecular mechanisms underlying GC metastasis. scRNA-seq ...

Single-cell technologies (e.g., scRNA-seq) are valuable techniques ... Furthermore, Slide-Seq and High Definition Spatial Transcriptomics (HDST) have effectively mapped gene expression at the ...

Single-cell RNA sequencing (scRNA-seq) approaches can provide transcriptomic profiles of individual cells isolated from brain tissue. However, the spatial context of these cells is vital to truly ...

One problem with this new approach is that scRNA-seq and spatial transcriptomics are expensive and have limited clinical applications as they are not routinely assayed as part of cancer diagnosis.

Among the different approaches, spatial transcriptomics has gained significant ... Single-cell methods such as scRNA-seq are key to studying the heterogeneity and dynamic changes of eukaryotic ...

For this visualization, scRNA-seq/snRNA-seq data were integrated by the Harmony algorithm, while downstream analyses were performed separately on scRNA-seq and snRNA-seq data to control for ...

Researchers mapped tissue remodeling during colitis development in mice to explore how diverse cell types contribute and respond to the disease. In this webinar, Pinaki Bose and Fei Chen will discuss ...

By isolating and sequencing the RNA from single cells, scRNA-Seq reveals the heterogeneity and dynamics of gene expression within cell populations. It is particularly useful for studying rare cell ...

Illumina is raising the curtain on its upcoming entry into spatial transcriptomics ... being held in Florida—where the DNA sequencing giant is set to unveil more details and demonstrations ...