ApoE3-rHDL 是一种重构的高密度脂蛋白，利用Apolipoprotein E3（ApoE3）作为表面修饰，以增强药物穿越血脑屏障（BBB）的能力，并靶向阿尔茨海默病（AD）中Aβ聚集区域。α-倒捻子素（α-M）是一种具有抗淀粉样蛋白（Aβ）聚集的活性物质。 由ApoE3重构的高密度脂蛋白 ...

Reconstituted HDL (rHDL) therapy in humans has resulted in regression of atheroma volume and plaque remodeling. The applications of rHDL appear vast as encouraging results in improving glucose ...

Figure. Schematic model of putative interfaces of high-density lipoprotein (HDL) and apolipoprotein A-I (apoA-I) with 3 specific human arthritic diseases. The model summarizes past literature and ...