C&EN1 个月
Intra-axonal Nanomagnetic Forces Differentially Impact hTau40 Transport Dynamics in Primary ...
Department of Electrical and Computer Engineering, Montana State University, Bozeman, Montana 59717, United States Montana Nanotechnology Facility, Montana State University, Bozeman, Montana 59717, ...
Frontiers8 个月
Calcium-dependent activator protein for secretion 2 is involved in dopamine release in ...
The Ca 2+-dependent activator protein for secretion (CAPS/CADPS) family protein facilitates catecholamine release through the dense-core vesicle exocytosis in model neuroendocrine cell lines. However, ...
eLife5 年
Degradation of engulfed mitochondria is rate-limiting in Optineurin-mediated mitophagy in ...
To investigate the extent of OPTN association with damaged mitochondria, we quantified the percent of OPTN puncta on linear (i.e. healthy) versus rounded (i.e. damaged) mitochondria. OPTN association ...
eLife5 年
Inhibition of synucleinopathic seeding by rationally designed inhibitors
The efficiency of capping inhibitors in preventing seeding was tested using a HEK293 cell-based assay. In this system, transfection of nanomolar amounts of α-syn seeds causes aggregation of the ...