This valuable study on Pseudomonas subverting host immunity identifies a new immune evasion strategy. There is solid evidence for the cleavage of VgrG2B by Caspase 11 and the generation of fragments ...

A Rac GTPase–regulated multiprotein NADPH oxidase is critical for the formation of reactive oxygen species (ROS) in phagocytic leukocytes and other nonphagocytic cells. NADPH oxidase reduces ...

Cell migration is central to a wide variety of physiological and pathophysiological processes. These include morphogenetic movements during embryogenesis, migration of inflammatory cells to sites of ...