Lurking within the genomes of nearly all species--including plants, fungi, and even humans--are genes that are passed from generation to generation with no clear benefit to the organism. Called ...

Researchers at the Stowers Institute discovered how selfish genes manipulate inheritance by forming toxic protein clusters. These genes, found in yeast, evolve rapidly to outpace genetic suppression ...

A genetic mutation in mice affects cells required for sexual reproduction and holds clues about male infertility that could pave the way for new treatments and male contraceptives, a Rutgers ...

Background: Non-SMC condensin I complex subunit G (NCAPG) is expressed in various human cancers, including gliomas. However, its biological function in glioma remains unclear. The present study was ...

This month's cover highlights the article Nup358 restricts ER-mitochondria connectivity by modulating mTORC2/Akt/GSK3β signalling by Joseph, Misha Kalarikkal and colleagues. The image shows a human ...

Qi Zhao et al. demonstrate that low-dose exposure to polystyrene microplastics (PSMPs) leads to severely abnormal reproduction in females, manifested by oocyte meiotic maturation defect.

Homologous recombination—a crucial meiotic event—not only enhances genetic diversity through exchanging parental genetic material but also establishes physical connections between homologous ...

2025年2月20日，国际顶级学术期刊《自然》（Nature）在线发表了上海交通大学医学院附属新华医院黄旲研究员团队与中国科学院分子细胞科学卓越创新中心童明汉课题组的合作研究成果——《体外重构减数分裂DNA双链断裂形成》（In vitro reconstitution of meiotic DNA double ...

In a study published in Nature, researchers report the successful in vitro reconstitution of meiotic DNA double-strand breaks (DSBs) formation. Meiosis, a specialized form of cell division in most ...

“In many of the meiotic mutants, instead of 0.2 percent males, you end up with 30 to 40 percent males. So, it's very easy to see,” she said. To zoom in on changes in chromosome organization during ...