Conversely, if the signaling pathway is activated by growth factors, mTOR complex 2, and, finally, PKN, the lipid kinase remains inactive and the mTOR complex 1 is able to drive cell growth.

A new signaling pathway for mTor-dependent cell growth Date: August 27, 2019 Source: Forschungsverbund Berlin Summary: A team led by the scientist has now discovered how inactivation of a certain ...

The mTOR pathway is probably the main pathway in humans and other animals that drives growth. That is, the accumulation of mass and adding mass to make an organism bigger by both making more cells ...

New preclinical research shows a promising drug combination that targets ovarian cancer’s survival pathways, paving the way ...

Phosphoinositide 3-kinase, AKT, and Mammalian Target of Rapamycin Signaling Pathway The PI3K/AKT/mTOR signaling pathway has been well characterized and recognized to play essential roles in normal ...

A recent study published in Genes & Diseases reveals a novel role of XPR1 in promoting ovarian cancer growth by regulating ...

'The consideration of aberrant PIK3/AKT/mTOR signaling in glia during aging elucidates several therapeutic opportunities for brain tumors'.

A pairing of two experimental drugs inhibits tumor growth and blocks drug-induced resistance in ovarian cancer, according to ...

A recent study published in Genes & Diseases reveals a novel role of XPR1 in promoting ovarian cancer growth by regulating ...

A newly published study in Genes & Diseases highlights the crucial role of the mammalian target of rapamycin (mTOR) pathway in the progression of diabetic nephropathy (DN) and explores its ...