Using quantitative proteomics, the authors uncover that ZMAT3 knockout leads to upregulation of HKDC1, a gene linked to mitochondrial respiration, and that ZMAT3 suppresses HKDC1 expression by ...

Explore the innovative applications of mRNA technologies beyond COVID-19 vaccines. Learn about the potential and future developments in this groundbreaking field.

Trans amplifying mRNA vaccine expressing consensus spike elicits broad neutralization of SARS CoV 2 variants. npj Vaccines , 2025; 10 (1) DOI: 10.1038/s41541-025-01166-1 Cite This Page : ...

Alternatively, the traditional RT-qPCR method can be used to quantify mRNA via reverse transcription and PCR amplification. Humoral immunogenicity. The Enzyme-Linked Immunosorbent Assay ...

Best practices in qPCR and dPCR assay design, validation and application; How to design and validate PCR assays for cell and gene therapy; Tips for optimizing assay performance and knowing when to use ...

Republican lawmakers and federal health officials alike are shunning messenger RNA, a basic building block of biology that proved its value during COVID, and that holds promise for combating the ...

The sharp turnaround on mRNA vaccines shows an unprecedented rise of anti-vaccine activists to power and an attack on accepted science.

A new type of mRNA vaccine is more scalable and adaptable to continuously evolving viruses such as SARS-CoV-2 and H5N1, according to a study by researchers at the University of Pittsburgh School ...

Tips for optimising and validating your multiplex qPCR assays Multiplex qPCR is a popular area of interest for many assay developers. Thanks to distinct reporter dyes, multiple reactions can be ...

The U.S. government is pulling its funding for drugmaker Moderna to continue testing an mRNA vaccine intended to protect people from the bird flu.