Using quantitative proteomics, the authors uncover that ZMAT3 knockout leads to upregulation of HKDC1, a gene linked to mitochondrial respiration, and that ZMAT3 suppresses HKDC1 expression by ...

Explore the innovative applications of mRNA technologies beyond COVID-19 vaccines. Learn about the potential and future developments in this groundbreaking field.

Multiplex qPCR is a popular area of interest for many assay developers. Thanks to distinct reporter dyes, multiple reactions can be combined into a single well, with each target detected independently ...

In an ambitious move, Moderna has teamed up with OpenAI, the artificial intelligence company behind ChatGPT, to further integrate generative AI (GenAI) across its mRNA drug development and ...

近期，国际SCI期刊《Journal of Ethnopharmacology》最新发表研究，为困扰众多女性的盆腔炎性疾病后遗症( Sequelae of pelvic infammatory disease, SPID )带来了治疗新希望！

近期，林爱福与周天华团队在人类胃癌等组织样本中鉴定出近万个尚未被充分解析的新型微肽，并借助人工智能技术对其功能进行了系统注释，为肿瘤等恶性疾病的预防和干预提供了新的靶点和思路。相关论文Comprehensive Discovery and ...

近期，浙江大学林爱福与周天华团队在人类 胃癌 等组织样本中鉴定出近万个尚未被充分解析的新型微肽，并借助人工智能（AI）技术对其功能进行了系统注释，为肿瘤等恶性疾病的预防和干预提供了新的靶点和思路。

高原多应激环境（低压缺氧、低温、强辐射）可导致认知障碍与肠道菌群失衡，但机制尚不明确。西藏大学等团队通过模拟海拔3500-4000米环境，发现约氏乳杆菌HL79能通过调节海马脂代谢基因（如CREB/BDNF通路）和血清代谢物（胆汁分泌、亚油酸代谢等），缓解小鼠空间记忆损伤和氧化应激。该研究为高原适应提供了基于微生物-肠-脑轴的新型干预策略，发表于《AMB Express》。

RNA modifications are changes to the chemical composition of ribonucleic acid (RNA) molecules post-synthesis that have the potential to alter function or stability. An example of RNA modification ...