在法医体液鉴定领域，传统方法存在诸多局限，mrna 检测法虽有优势但也有不足。研究人员对比 rt-lamp+crispr-cas12a 与两种 mrna 检测法。结果显示 rt-qpcr 综合性能最佳，rt-lamp+crispr-cas12a 特异性高但灵敏度有限。该研究为法医体液鉴定提供参考。

体外转录报告荧光素酶 mrna：用于体外转录的 dna 质粒经线性化、纯化后，作为模板在含有多种转录相关酶和核苷酸的反应体系中进行转录，转录后添加 7 - 甲基鸟苷酸帽，再经纯化、定量后得到用于实验的 mrna。 逆转录和 qpcr：从体外翻译反应中提取 rna，经逆转 ...

MammaTyperRT-qPCR与IHC检测乳腺癌 ER/PR/Ki67/HER2-low之间显示出高度一致性。. 目前，尽管多基因检测技术在乳腺癌的诊断和治疗中扮演着越来越重要的角色 ...

药明康德内容团队编辑（来源：中国科学院动物研究所）mRNA疗法因研发周期短、生产成本低、制备工艺简单、起效快等优势，被广泛应用于疫苗研发 ...

实验室利用全自动化系统快速生产mRNA，以推动大规模的临床前研究，并开发新的mRNA疫苗和其他相关疗法。 这个实验室是新科研9700万元的核酸药物开发计划（Nucleic Acid Therapeutics Initiative，简称NATi）中的一部分，目标是让新加坡成为核糖核酸（RNA）药物和疫苗研究、临床转化和商业化的区域节点。

That’s because, for mRNA-based Covid-19 vaccines like those developed by Pfizer/BioNTech and Moderna, a shot in the arm did the trick. But in cases where mRNA is harnessed for other uses ...

Trans amplifying mRNA vaccine expressing consensus spike elicits broad neutralization of SARS CoV 2 variants. npj Vaccines , 2025; 10 (1) DOI: 10.1038/s41541-025-01166-1 Cite This Page : ...

China's CanSino Biologics Inc has entered "test production phase" for its COVID-19 mRNA booster vaccine, the company said in a post on its social media account late on Thursday.

A pharmacist administers a COVID-19 vaccination booster shot to a customer. Getty Images. The study showed a 16.3-fold increase in antibodies for the mRNA RBD-TM vaccine compared with 1.3 for the ...

But the self-amplifying mRNA shot did elicit antibodies in a greater percentage of people than Comirnaty. And a month out, antibody levels against Omicron BA.4/5 were higher in people who received ...

China approved its first messenger RNA vaccine for Covid-19, clearing a shot from a local drugmaker that harnesses the powerful technology months after the world’s most-populous nation abandoned ...

China has for the first time approved a Covid-19 vaccine based on mRNA technology, greenlighting a homegrown shot months after the ruling Communist Party eliminated its strict pandemic restrictions.