US clinical-stage biotech Vigil Neuroscience (Nasdaq: VIGL) today announced a disappointing update on the Phase II IGNITE ...

Vigil on Wednesday said it is ending a Phase 2 study of iluzanebart in patients with adult-onset leukoencephalopathy with axonal spheroids and pigmented glia, or ALSP, after the drug showed no ...

Vigil Neuroscience, Inc. (Nasdaq: VIGL), a clinical-stage biotechnology company committed to harnessing the power of ...

蛇咬伤后常出现神经毒性表现，为明确儿科患者蛇咬伤后是否存在特殊神经并发症，研究人员对相关病例开展研究。发现 1 例 3 岁患儿蛇咬伤后经 ASV 治疗仍出现癫痫等症状，MRI 显示多灶性白质病变，提示临床需关注蛇咬伤诱导的白质脑病。

Progressive multifocal leukoencephalopathy (PML) is a fatal demyelinating disease of the central nervous system caused by lytic infection of oligodendrocytes by pathogenic strains of the JC ...

Josef-Hospital, Ruhr University Bochum, Gudrunstr. 56, Bochum 44791, Germany; ralf.gold{at}rub.de Objective Although the prognosis of natalizumab-associated progressive multifocal leukoencephalopathy ...

Less than two weeks after Loris Beckles moved to Dallas, his partner died of complications from AIDS. Andre R. George had ...

The High Court in England has granted a significant interim payment to Louise Hill for essential living adjustments ...

Vigil Neuroscience tripled Thursday after Sanofi agreed to buy it for $470 million plus a CVR tied to its experimental ...

st-vincents.ie The use of natalizumab for highly active relapsing-remitting multiple sclerosis (MS) is influenced by the occurrence of progressive multifocal leukoencephalopathy (PML). Through ...

Here, using an organoid system, Wong et al aimed to establish new models of hereditary diffuse leukoencephalopathy with axonal spheroids (HDLS), with which they wanted to understand how CSF1R-mutaions ...

The work will be of interest to neuroscientists and clinicians aiming to understand and combat similar neurodegenerative disorders. Hereditary diffuse leukoencephalopathy with axonal spheroids (HDLS) ...