The following is a summary of “Disruption of the sorcin‒PAX5 protein‒protein interaction induces ferroptosis by promoting the FBXL12-mediated ubiquitination of ALDH1A1 in pancreatic cancer,” published ...

Genentech Inc. has disclosed molecular glue compounds with the ability to induce cyclin-dependent kinase 2 (CDK2)/protein cereblon (CRBN) interaction for CDK2 degradation reported to be useful for the ...

NDA submission based on results from Phase 3 DUPLEX and Phase 2 DUET studies of FILSPARI in FSGS If approved, FILSPARI could become the first and only FDA-approved treatment for FSGS, a rare kidney ...

NDA submission based on results from Phase 3 DUPLEX and Phase 2 DUET studies of FILSPARI in FSGSIf approved, FILSPARI could become the first and ...

Proxygen GmbH has divulged molecular glue degraders comprising a cullin-ring E3 ligase (CRL)-binding moiety acting as cyclin-dependent kinase 12 (CDK12)/cyclin K degradation inducers reported to be ...

The following is a summary of “Naldemedine Use and Healthcare Resource Utilization in Patients treated with Opioid Analgesics for Chronic Non-Cancer Pain: Results of a Real-world Study in the USA,” ...

In a live event, Ganesh V. Raj, MD, PhD, discussed the drug-drug interactions and outcomes by disease volumes across ARPI trials in mHSPC.

The results identified plant resistance inducers (PRIs) among biopesticide products capable of protecting carrots against Alternaria leaf blight. By applying a PRI to a range of carrot varieties ...

Company to Roll Out Availability of IMKELDI (imatinib) for Patients with Certain Forms of Leukemia and Other Cancers Shorla Oncology ('Shorla'), a U.S.-Ireland specialty pharmaceutical company, ...

If taking both, watch for an increase in buspirone-related side effects. Certain antiepileptic drugs may interact with buspirone. These drugs are enzyme inducers, meaning they increase the metabolic ...

Phosphaturic mesenchymal tumor (PMT) is an extremely rare neoplasm that causes tumor-induced osteomalacia (TIO) in most affected patients, usually through the production of fibroblast growth factor 23 ...